What is a radical neck dissection? when is it done?

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What is a radical neck dissection? The surgeon removes a block of tissue from the collarbone to the jaw and from the front to the back of the neck. The large muscle on the side of the neck that is used for rotating, flexing or extending the neck is also taken out, along with the major vein on the side of the neck. Sometimes, a less drastic operation, called a supraomohyoid neck dissection is done. This takes out only the lymph nodes, the tissue surrounding the nodes and a muscle at the front of the neck. Another technique, called a functional neck dissection, saves the muscles of the neck, taking out only the lymph nodes and tissues surrounding them.
What kind of incision is made with a radical neck dissection? The incision depends upon what the surgery is for. It can run from below the ear to the collarbone. Everything in the front of the neck on one side or on both sides may be removed. This may include the lymph nodes, blood vessels, nerves, and the salivary gland under the jawbone.

How do statins work to lower cholesterol in the body?

How do statins work? 

Understanding how statins work will help you understand their possible adverse effects. Statins interfere with the production of cholesterol in the body, mainly in the liver. Since you synthesize your own cholesterol, it makes sense to limit the amount you consume if you are an overproducer. The liver together with cholesterol from food is responsible for most of the cholesterol found in the blood. There is a key step in cholesterol synthesis that these statins block quite effectively. The result is a reduction in blood LDLcholesterol levels of 25 percent to 45 percent, depending on the dose prescribed.

Since cholesterol is the key molecule for the production or synthesis of other essential compounds (like some hormones and bile acids needed for the digestion of fats) in the body, if the dose of the statin is too high there may be some adverse effects.

Statins and Cholesterol

Always remember: do as much as possible in terms of diet, not smoking, physical activity, and stress management so that if you still need a statin or any other cholesterol lowering drug a low dose will be effective.

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